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Geriatric Integrated Medicine: Inflammation

Topic Information

Inflammation: An immunological defense against injury, infection, or allergy, marked by increases in regional blood flow, immigration of white blood cells, and release of chemical toxins. Inflammation is one way the body uses to protect itself from invasion by foreign organisms and to repair wounds to tissue. Clinical hallmarks of inflammation are redness, heat, swelling, pain, and loss of function of a body part. Systemically, inflammation may produce fevers, joint and muscle pains, organ dysfunction, and malaise. 

Source: Taber's Medical Dictionary Online

Research from PubMed


Impact of resistance training on the autophagy-inflammation-apoptosis crosstalk in elderly subjects.


Mejías-Peña Y, Estébanez B, Rodriguez-Miguelez P, Fernandez-Gonzalo R, Almar M, de Paz JA, González-Gallego J, Cuevas MJ.


Aging (Albany NY). 2017 Feb 2;9(2):408-418. doi: 10.18632/aging.101167.


PMID: 28160545 [PubMed - indexed for MEDLINE] Free PMC Article


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Structural brain changes and all-cause mortality in the elderly population-the mediating role of inflammation.


Hanning U, Roesler A, Peters A, Berger K, Baune BT.


Age (Dordr). 2016 Dec;38(5-6):455-464. doi: 10.1007/s11357-016-9951-9. Epub 2016 Oct 20.


PMID: 27766478 [PubMed - indexed for MEDLINE] Free PMC Article


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Inflammation and frailty in the elderly: A systematic review and meta-analysis.


Soysal P, Stubbs B, Lucato P, Luchini C, Solmi M, Peluso R, Sergi G, Isik AT, Manzato E, Maggi S, Maggio M, Prina AM, Cosco TD, Wu YT, Veronese N.


Ageing Res Rev. 2016 Nov;31:1-8. doi: 10.1016/j.arr.2016.08.006. Epub 2016 Aug 31. Review.


PMID: 27592340 [PubMed - indexed for MEDLINE] Free Article


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Quantile Regression Analysis of the Distributional Effects of Air Pollution on Blood Pressure, Heart Rate Variability, Blood Lipids, and Biomarkers of Inflammation in Elderly American Men: The Normative Aging Study.


Bind MA, Peters A, Koutrakis P, Coull B, Vokonas P, Schwartz J.


Environ Health Perspect. 2016 Aug;124(8):1189-98. doi: 10.1289/ehp.1510044. Epub 2016 Mar 11.


PMID: 26967543 [PubMed - indexed for MEDLINE] Free PMC Article


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Relationship between inflammation and oxidative stress and cognitive decline in the institutionalized elderly.


Baierle M, Nascimento SN, Moro AM, Brucker N, Freitas F, Gauer B, Durgante J, Bordignon S, Zibetti M, Trentini CM, Duarte MM, Grune T, Breusing N, Garcia SC.


Oxid Med Cell Longev. 2015;2015:804198. doi: 10.1155/2015/804198. Epub 2015 Mar 19.


PMID: 25874023 [PubMed - indexed for MEDLINE] Free PMC Article


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The influence of systemic inflammation on skeletal muscle in physically active elderly women.


Wåhlin-Larsson B, Carnac G, Kadi F.


Age (Dordr). 2014;36(5):9718. doi: 10.1007/s11357-014-9718-0. Epub 2014 Oct 14.


PMID: 25311555 [PubMed - indexed for MEDLINE] Free PMC Article


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Persistent inflammation and T cell exhaustion in severe sepsis in the elderly.


Inoue S, Suzuki K, Komori Y, Morishita Y, Suzuki-Utsunomiya K, Hozumi K, Inokuchi S, Sato T.


Crit Care. 2014 Jun 24;18(3):R130. doi: 10.1186/cc13941.


PMID: 24962182 [PubMed - indexed for MEDLINE] Free PMC Article


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Unexplained anaemia in the elderly is characterised by features of low grade inflammation.


Artz AS, Xue QL, Wickrema A, Hesdorffer C, Ferrucci L, Langdon JM, Walston JD, Roy CN.


Br J Haematol. 2014 Oct;167(2):286-9. doi: 10.1111/bjh.12984. Epub 2014 Jun 17. No abstract available.


PMID: 24935746 [PubMed - indexed for MEDLINE] Free PMC Article


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